Conversion of haemodialysis patients from iron sucrose to iron isomaltoside: a real-world experience
نویسندگان
چکیده
منابع مشابه
A randomized trial of iron isomaltoside versus iron sucrose in patients with iron deficiency anemia
Iron deficiency anemia (IDA) is common in many chronic diseases, and intravenous (IV) iron offers a rapid and efficient iron correction. This trial compared the efficacy and safety of iron isomaltoside and iron sucrose in patients with IDA who were intolerant of, or unresponsive to, oral iron. The trial was an open-label, comparative, multi-center trial. Five hundred and eleven patients with ID...
متن کاملA randomized, open-label trial of iron isomaltoside 1000 (Monofer®) compared with iron sucrose (Venofer®) as maintenance therapy in haemodialysis patients
BACKGROUND Iron deficiency anaemia is common in patients with chronic kidney disease, and intravenous iron is the preferred treatment for those on haemodialysis. The aim of this trial was to compare the efficacy and safety of iron isomaltoside 1000 (Monofer®) with iron sucrose (Venofer®) in haemodialysis patients. METHODS This was an open-label, randomized, multicentre, non-inferiority trial ...
متن کاملIntroducing iron isomaltoside 1000 (Monofer®)-development rationale and clinical experience.
Patients with chronic kidney disease (CKD) often suffer from iron deficiency anaemia necessitating treatment with intravenous (IV) iron. Several studies demonstrate that oral iron is insufficient in these patients and that IV supplementation is a more effective treatment. Until now, use of available parenteral iron preparations has been limited by dosing schedules and the need, in some cases, f...
متن کاملImpact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients.
BACKGROUND It has been suggested that iron increases oxidative stress and that an excess of iron contributes to cardiovascular disease and infections in haemodialysis patients. In the present study, the effects of parenterally administered iron on leucocyte surface molecule expression and the production of reactive oxygen species (ROS) were evaluated. METHODS Ten chronic haemodialysis (HD) pa...
متن کاملReal-world use of iron chelators.
Whereas RBC transfusion therapy is lifesaving in thalassemia, obligatory iron loading accompanies such treatment and chelation therapy to remove and detoxify iron resulting from these chronic transfusions must therefore be administered. Morbidity and mortality in thalassemia is linked closely to the adequacy of chelation. Three chelators are currently available worldwide-deferoxamine, deferasir...
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ژورنال
عنوان ژورنال: BMC Nephrology
سال: 2020
ISSN: 1471-2369
DOI: 10.1186/s12882-020-01866-x